Antibacterial and remineralization effects of orthodontic bonding agents containing bioactive glass
김유민, 김동현, Song Chang-Weon, Yoon Seog-Young, 김세연, 나희삼, 정진, 김용일, 권용훈,
소속 상세정보
김유민 ( Kim You-Min ) - Pusan National University Dental Hospital Department of Orthodontics
김동현 ( Kim Dong-Hyun ) - Upex-med Co. Ltd.
( Song Chang-Weon ) - Pusan National University School of Materials Science and Engineering
( Yoon Seog-Young ) - Pusan National University School of Materials Science and Engineering
김세연 ( Kim Se-Yeon ) - Pusan National University School of Dentistry Department of Oral Microbiology
나희삼 ( Na Hee-Sam ) - Pusan National University School of Dentistry Department of Oral Microbiology
정진 ( Chung Jin ) - Pusan National University School of Dentistry Department of Oral Microbiology
김용일 ( Kim Yong-Il ) - Pusan National University Dental Hospital Department of Orthodontics
권용훈 ( Kwon Yong-Hoon ) - Pusan National University Department of Dental Materials
Abstract
Objective: The aim of this study was to evaluate the mechanical and biological properties of orthodontic bonding agents containing silver- or zinc-doped bioactive glass (BAG) and determine the antibacterial and remineralization effects of these agents.
Methods: BAG was synthesized using the alkali-mediated solgel method. Orthodontic bonding agents containing BAG were prepared by mixing BAG with flowable resin. Transbond™ XT (TXT) and Charmfil™ Flow (CF) were used as controls. Ion release, cytotoxicity, antibacterial properties, the shear bond strength, and the adhesive remnant index were evaluated. To assess the remineralization properties of BAG, micro-computed tomography was performed after pH cycling.
Results: The BAG-containing bonding agents showed no noticeable cytotoxicity and suppressed bacterial growth. When these bonding agents were used, demineralization after pH cycling began approximately 200 to 300 μm away from the bracket. On the other hand, when CF and TXT were used, all surfaces that were not covered by the adhesive were demineralized after pH cycling.
Conclusions: Our findings suggest that orthodontic bonding agents containing silver- or zinc-doped BAG have stronger antibacterial and remineralization effects compared with conventional orthodontic adhesives; thus, they are suitable for use in orthodontic practice.
키워드
Bioactive glass; Adhesive; Antibacterial; Remineralization
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